Thyrotropin-releasing hormone
Thyrotropin-releasing hormone (TRH) is a tripeptide hormone
produced by the hypothalamus and stimulating production of TSH and
prolactin by the anterior lobe of the pituitary. It is passed from the hypothalamus (eminentia mediana) to the pituitary by
means of the pituitary portal system.
The sequence of TRH was first determined and the hormone was synthetised by
Roger Guillemin and Andrew V. Schally in 1969.
The presence of TRH can also be detected in other parts of the brain, in the gastrointestinal system and pancreatic islets.
Medical preparations of TRH are used in diagnostic tests of thyroid disorders
and in acromegaly.
Structure : (pyro)Glu-His-Pro-NH2
Molecular weight : 359,5 D
Referenced By
Acronym/Medical List | List of human blood components | List of medical abbreviations | List of medical acronyms | Thyroid-stimulating hormone | Thyroid stimulating hormone | Thyrotropin
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