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Hershey-Chase experiment
In 1952, Alfred Hershey and Martha Chase conducted a series of experiments that identified DNA to be the genetic material of phages and, ultimately, of all organisms.
A phage is a small virus that infects bacteria. It consists of a protein coat that encloses the genetic material. When a phage infects a bacterium, it inserts its genetic material into the bacterium, while its coat remains outside.
In a first experiment, T2 phages with radioactive 32P-labeled DNA infected bacteria. In a second experiment, T2 phages with radioactive 35S-labeled protein infected bacteria. In both experiments, bacteria were separated from the phage coats by blending followed by centrifugation. In the first experiment, most radioactivity was found in the infected bacteria, while in the second experiment most radioactivity was found in the phage coat. These experiments demonstrated that DNA is the genetic material of phage and that protein does not transmit genetic information.
Referenced By
Cold Spring Harbor Laboratory | Famous Experiments | Geneticist | Genetics | Griffith's experiment | Griffith's experiment (genetics) | Griffiths experiment | List of Famous Experiments | List of biological topics | List of biology topics | Marsha Chase | Martha Chase | Oswald Avery | Oswald Theodore Avery | Transforming principle
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Hershey-Chase experiment
Anonymous - September 27th, 2005
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A centrifuge is a device for applying force to a sample, usually by motor driven rotary motion of the sample. There are many different kinds of centrifuges, often for very specialized purposes.
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Hershey-Chase experiment
Anonymous - September 27th, 2005
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Genetic material is the material used to store genetic information for a living organism.
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Hershey-Chase experiment
Anonymous - September 27th, 2005
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In a first experiment, T2 phages with radioactive 32P-labeled DNA infected bacteria. In a second experiment, T2 phages with radioactive 35S-labeled protein infected bacteria. In both experiments, bacteria were separated from the phage coats by blending followed by centrifugation. In the first experiment, most radioactivity was found in the infected bacteria, while in the second experiment most radioactivity was found in the phage coat. These experiments demonstrated that DNA is the genetic material of phage and that protein does not transmit genetic information.
read more » messages 1
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